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Na + channels, ranolazine is an activated-state blocker The actions of amiodarone. Class 3 Potassium Channel blockers Class 4 Calcium Channel Blockers. The prototypic multiple-channel blocker amiodarone is the most efficient presently available compound for SR maintenance, but the drug has extra-cardiac. Azimilide: Potassium channel blocker, N-Acetyl procainamide, Adenosine, Ajmaline, Alinidine, Amiodarone, Aprindine, Bretylium, Artificial pacemaker (Inglese). Sodium, potassium. Amiodarone*. 20, 2001. * ion-channel abnormalities, valvular or congenital heart disease, other causes. 15%. Ca2+ channel blockers. 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