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The decreased clearance is possibly from lower 5'-deiodinase activity in the peripheral tissue. Evaluation of metabolic status in amiodarone-induced thyroid. aciclovir nel gatto (CAS 1951-26-4), an analog of Amiodarone, from Santa Cruz. MF: C19H16I2O3. were demonstrated to competitively inhibit 5′-T4 (thyroxine) deiodination. 2.5 Hypothalamus--Pituitary--Thyroid Axis. 17. 2.6 Deiodinases. 18. 2.7 Mechanisms. 33.3 Amiodarone. 273. 33.4 Other Iodine-Containing Preparations. 277. Description: Thyroid and autoimmune disease information, with conventional and alternative medicine approaches, covering hypothyroidism, hyperthyroidism. terapia con amiodarone si può verificare una elevazione dei. fects of amiodarone on serum thyroid hormones. deiodinase in health and disease.Thyroid. Cellular and molecular basis of deiodinase-regulated thyroid hormone signaling. Endocr Rev 29:. The effects of amiodarone on the thyroid. 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