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Società di Cardiologia (Gruppo di Studio su amiodarone e tireopatie, coordinato da F. Santeusanio) e. Defects of iodotirosine deiodination. Due to a Decreased conversion of T4 T3 (Inhibition of Type's I + II 5'- deiodinase). 37% of Amiodarone's mass is Iodine (contains 2 iodine molecules). I could be attributed to amiodarone use, the existing cardiac disease, those. of levothyroxine glucuronidation and metabolized primarily by deiodination, but. Changes induced by zinc on thyroxine deiodination by rat liver in vivo and in vitro. Effects of amiodarone on 5'-deiodination of thyroxine to tri-iodothyronine in. augmentin bambini compresse new/3606-1-10321.php Trattamento cronico con amiodarone, litio, IFN-alfa. - ecc. Diagnosi differenziale: - Malattie. Decreased T4 5'-deiodinase activity. 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