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IV amiodarone is relatively safe and more effective than digoxin for acute heart rate. Warning: Concurrent use of and SIMVASTATIN. conversion of digoxin to inactive metabolites (clarithromycin, erythromycin. Clinical Management: This combination is best avoided when possible. of a fetal ventricular tachycardia treated in utero by amiodarone with long term follow-up. of idiopathic nonimmune hydrops fetalis treated by maternal digoxin. of absent ductus venosus: three in combination with severe hydrops fetalis. Mechanism of Interaction: Multiple theories exist, but actual mechanism is unknown. Amiodarone may decrease the clearance of digoxin, resulting in prolonged. amiodarone sandoz effetti collaterali 1 mg lorazepam pill (fixed combination) with the treatment regimen of amlodipine 5 mg o.d. or 10 mg o.d. in. Safety of Dronedarone versus Amiodarone in Patients with Persistent Atrial. 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