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Lymphoid Hyperplasia and Eosinophilic Pneumonia as Histologic Manifestations of Amiodarone-induced Lung Toxicity. Amiodarone (AD) has been shown to produce a transient pulmonary fibrosis in. in lavage macrophage, neutrophil, and eosinophil number through Day 28. 3, One case of immune-mediated amiodarone (A) pneumonitis, 1986, PESCI A;. 17, I mastociti nelle vie aeree di pazienti affetti da farmer's lung, 1991, PESCI A;. 20, MAST-CELLS AND EOSINOPHILS IN BRONCHIAL-ASTHMA, 1991. RESULTS: Gene expression profiling showed that eosinophils appear. 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