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Peripheral nervous system changes were seen with EMG and nerve. doses of amiodarone Elektronische Ressource 1989 Neurological sciences 10 (1989). Signs and symptoms of peripheral neuropathy were evaluated clinically and. (amiodarone, bretilio, dofetilide, ibutilide, sotalolo*). Classe IV:. bluish skin, hypo- or hyper-thyroidism, peripheral neuropathy, elevated transaminases. Toxic and nutritional optic neuropathies resemble each other in terms of their clinical. or toxic peripheral neuropathy a related toxic cerebellar degeneration. In amiodarone-induced optic neuropathy, the onset of visual loss is much. Food shortages and an epidemic of optic and peripheral neuropathy in Cuba. Nutr Rev 1993. Optic neuropathy and amiodarone therapy. 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