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OPTIC Study: Amiodarone Plus Beta-Blocker Reduces ICD Shocks. significantly fewer ICD shocks if they are given a combined drug regimen consisting of. Sotalol was given alone because it has both antiarrhythmic and. Pacemaker impulse formation; Impulse conduction; Combination of the two. (amiodarone, bretilio, dofetilide, ibutilide, sotalolo*). 30-min, 2 mg dosing or ensuing 30-40 minutes; More effective than iv procainamide or sotalol; Adverse effect:. 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La contemporanea assunzione di AMIODARONE e BLOCCANTI. Concurrent use of ISOTRETINOIN and CONTRACEPTIVES, COMBINATION. Concurrent use of EPINEPHRINE and SOTALOL may result in hypertension, bradycardia.
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