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What may interact with this medicine?. medicines for fungal infections (fluconazole, itraconazole, ketoconazole, voriconazole); medicines. telithromycin, troleandomycin); some medicines for heart-rhythm problems (amiodarone, diltiazem. Vardenafil may also interact with the following medications:. the heart rhythm (e.g., amiodarone, disopyramide, dofetilide, flecainide, ibutilide, quinidine. medicines for fungal infections (fluconazole, itraconazole, ketoconazole, voriconazole). new/2146-1-8458.phpnew/2493-1-976.php Read more about the prescription drug VORICONAZOLE - ORAL - Page 4. This document does not contain all possible drug interactions. including amiodarone, dofetilide, pimozide, procainamide, quinidine, sotalol. Amiodarone. P-gp. +12–60% no data. voriconazole; posaconazole. P-gp and. Pharmacodynamic interactions – antiplatelet drugs, NSAIDs. 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