new/842-1-14465.php combination and amlodipine. parallel-group comparison of valsartan and amlodipine in the treatment of isolated. new/8492-1-7819.php Titolo originale: Amlodipine-Valsartan Combination Decreases Central Systolic Blood Pressure More Effectively Than the Amlodipine-Atenolol Combination. Information on the drug amlodipine and valsartan (Exforge). DRUG CLASS AND MECHANISM: Exforge is a combination of two drugs used. The Valsartan Antihypertensive Long-term Use Evaluation (VALUE) trial was designed to. regimens based on valsartan or amlodipine would have differing effects on. Subsequent combined cardiac events, myocardial infarction, stroke, and. Exforge is a fixed combination of amlodipine and valsartan. 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