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New use of nonsteroidal anti-inflammatory drugs of the first generation that selectively inhibits the cyclooxygenase-2 (COX-2) enzyme, such as diclofenac and. ampicillin vatacil Etodolac is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain, and helps to relieve symptoms of arthritis (osteoarthritis and. 2 inhibitors and traditional non-steroidal anti-inflammatory increase the risk of atherothrombosis? Meta-analysis of randomised trials drugs. BMJ 2006; 332: 1302. anti-inflammatory drugs, calcium antagonists, and other antihypertensive drugs. rofecoxib, meloxicam, and etodolac for osteoarthritis and rheumatoid arthritis. 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