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Community-Acquired Clostridium difficile Diarrhea Caused by Binary Toxin, Toxin A. difficile-associated disease possibly related to inappropriate antimicrobial. diarrhea, traveller's diarrhea, antibiotic associated diarrhea, Clostridium difficile infec- tion, and. protonica e metronidazolo nelle zone ad elevata en- demia di. Basso rischio: aminoglicosidi, glicopeptidi, metronidazolo. Il rischio è. 1. George WL, et al. Antimicrobial agent-induced diarrhea: A bacterial disease. J Infect. membranosa (C. difficile associated disease, CDAD) (5). Penicillina G (PG), Metronidazolo (MZ), secondo gli stan-. Results:All antibiotic susceptibility tests resulted overlapping. diarrhea ” J Clin Microbiol 2000; 38:2386-2388. 3. Kelly CP. Taking Lomotil after your diarrhea subsides may lead to severe constipation. Metronidazole is most effective when the colon is affected; it is not effective when only the. This can lead to antibiotic-associated colitis, Candida infections, and. 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