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Cetirizine In Early Pregnancy. Cetirizine is in a class of drug known as an antihistamine also called anti-pruritic. Cetirizine Hydrochloride During Pregnancy. He prescribed Cetirizine Hydrochloride which is apparently one of the. if anyone has used this, or any other antihistamines whilst pregnant. new/4931-1-15974.php Thankfully, my current regimen of cetirizine and Zantac really helps cut down on. but was able to manage it with only Benadryl and more antihistamines. Abdominal angiodema (zero to eleven months pregnant in as little as a minute). new/5640-1-10045.php Zyrtec is an antihistamine used to treat both seasonal and perennial allergy. Cetirizine is also used to treat hives. Do not take Zyrtec without first talking to your doctor if you are pregnant or could become pregnant during treatment. Cetirizine. 1987. 2000+. <1970. 19s. 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