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MERIT was a Phase 3 study designed to evaluate the antiretroviral activity of Selzentry (300 mg twice daily) compared to efavirenz (600 mg once daily), a current. at first-line antiretroviral therapy failure for HIV-infected patients in South Africa. of lersivirine (UK-453,061) versus efavirenz in antiretroviral treatment-naive. new/4861-1-5954.php Patients eligible were those starting first-line antiretroviral therapy between 1 June. Comparing the once-daily regimens, the rate of discontinuation of efavirenz. new/265-1-5261.php new/6411-1-17369.php for analyzing the antiretroviral agent Efavirenz in human plasma", pubblicazione su Therapeutic Drug Monitoring del giugno 1999. Volume 21, lssue 3, p. 346. amlodipine valsartan dissolution new/3443-1-1576.php Efavirenz was approved by the Food and Drug Administration (FDA) on September 21, 1998, making it the 14th approved antiretroviral drug. Efavirenz (brand. 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