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The novel atypical antipsychotic agent aripiprazole is a partial agonist at D2 receptors that has been shown in clinical trials to be effective in treating both the. Repeated aripiprazole treatment regulates Bdnf, Arc and Npas4 expression under basal condition as well as after an acute swim stress in the rat brain. Unmet needs in the treatment of schizophrenia: the role of aripiprazole. antipsychotic, is considered to be a “third generation” compound, being a partial agonist at dopamine D2 and at serotonin 5-HT1A receptors and an antagonist at. Matches 1 - . Whereas all previously available antipsychotics are antagonists at D2 receptors, aripiprazole is the only available partial agonist at these. Why Abilify is a dopaimine partial agonist whilst for example Seroquel is a dopamine antagonist? What is the differences in effect? Is a partial. Le proprietà di parziale agonista D2 dell'aripiprazolo contribuiscono a stabilizzare più che. 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