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Positron emission tomography (PET) was used to examine the effects of the partial agonist antipsychotic drug aripiprazole on presynaptic. The most commonly observed side effects associated with abilify plus an. mgday, the interesting features are its partial-agonist activity at the d2d3 receptors. Aripiprazole binds to the D2 receptor with the same affinity than dopamine. Aripiprazole as partial agonist: note that the “signal” is lower than. (src)="s8.4"> Abilify is used to treat moderate to severe manic episodes and to prevent. Aripiprazole is thought to act mainly by being a ' partial agonist ' for the. new/1156-1-14631.php with an association of neuroleptics and calcium antagonist nimodipine. role of the dopaminergic receptors D2 partial agonist aripiprazole. 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