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20) Asymptomatic QTc prolongation during coadministration of aripiprazole and haloperidol. Leo R, Razzini C, Di Lorenzo G, Bianchi F. Aim of this study is to evaluate the QTc in the real world, where psychotic Pts are still treated with typical APDs. 6 months with APDs (haloperidol n=43, risperidone n=41, aripiprazole n=42. Pts with family history of SD or treated with QTc altering drugs were excluded. P03-63 - QT prolongation: Which psychotropics? [Risk of QTc prolongation due to combination of ziprasidone and quetiapine]. The relationship between clinical pharmacokinetics of aripiprazole and CYP2D6. Cardiac safety review of aripiprazole in somatic high-risk patients. aripiprazole was not associated with QTc prolongation. However, a. Practice Points Screen patients for risk factors for prolonged QTc interval, such. evidence that aripiprazole may shorten, rather than prolong, the QTc interval. 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