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Other clinical adverse and cause glucose intolerance, while estrogens may create a state of hyperinsulinism Glucose-Induced Phosphatidylinositol 3-Kinase and Mitogen-Activated. for cardiovascular disease in diabetes and impaired glucose tolerance. A prospective, randomized, comparison of the long-term effects of atenolol vs. nebivolol. Mild glucose intolerance in pregnan-. sion study (LIFE): a randomised trial against atenolol. fects of Ranolazin with Atenolol, Amlodipine, or Diltiazem on. Glucose intolerance appeared after 5 days of CPH treatment without significant. with the alpha-1 antagonist prazosin and the beta-1 antagonist atenolol. Mellitus by Changes in Lifestyle among Subjects with Impaired Glucose Tolerance. Efficacy of atenolol and captorpil in reducing risk of macrovascular and. Glucose tolerance and blood pressure: long term follow up in middle aged men. reduction in hypertension study (LIFE): a randomized trial against atenolol. 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