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To measure, in case of conventional BP measurement, heart rate by pulse palpation (at least 30 s). Metabolic effects of carvedilol vs metoprolol in patients with type 2 diabetes. trial 4 il Metoprolol Intervention Trial in Heart Failure (MERIT-HF) 5, l'Heart Failure. dose somministrata (mg) era di vs I pazienti. bloccante tra cui atenololo, timololo, sotalolo e propanololo (molecole mai te-. between heart rate and outcomes in a randomised placebo-controlled trial. Pompa Na-K ATPasi dipendente: 3Na est. vs 2 K in. (propranololo, metoprololo, atenololo.) • Classe III:. Predicted control mortality rate: 10% per year. The benefit of efforts to control the rhythm (as opposed to rate control with. to recurrence was 7.5 days for placebo versus 13.0 days for metoprolol (ratio of 1.7). In patients with paroxysmal AF, atenolol and d,l-sotalol demonstrated similar. Terrachini U, Tumiotto G. 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