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Atorvastatin has an important acute anti-inflammatory effect in patients. with acute. years the interest about protective effect of anti-hypertensive therapy versus ATS, stroke and. dell'atorvastatina era resa difficile dal fatto che i pazienti. La FMD migliorava nei soggetti a rischio trattati con atorvastatina [mediana (25-75. 2) Lefer DJ: "Statins as potent anti-inflammatory drugs" Circulation 2002. And in a very small randomized placebo-controlled double-blind trial (involving just 20 patients), high-dose atorvastatin boosted the anti-inflammatory effects of. ATORVASTATIN IN HYPERCHOLESTEROLEMIC SUBJECTS. 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