Be sure to document a normal G6PD level before prescribing primaquine. Travelers. Not recommended for people on atovaquone-proguanil prophylaxis. When chloroquine, doxycycline, or mefloquine is used for primary prophylaxis. Reyburn H, Mbatia R, Drakeley C, Carneiro I, Mwakasungula E, Mwerinde O, et al. (Malarone). Cannot be used in areas with chloroquine or mefloquine resistance; May exacerbate psoriasis. Doxycycline. Primaquine. 5 gocce di alprazolam raga For countries where chloroquine-resistant malaria occurs, which includes most. mefloquine (Lariam), (Malarone)(PDF), or doxycycline. Mefloquine is given once weekly in a dosage of 250 mg, starting one-to-two. 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