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Today) -- Cost analysis modeling appears to show that allopurinol (Zyloprim) is less expensive than the newer urate-lowering gout therapy febuxostat (Uloric). alfuzosin uno 10 mg Takeda's Uloric, which reached the market in 2009, managed to steal only about 10% of allopurinol's patient share, as the much lower cost and. Learn about the prescription medication Zyloprim (Allopurinol), drug uses, dosage, side effects, dru. Uloric (Febuxostat) Drug Information: Description, User. 24, 2008 -- Uloric should be the first new gout drug to be approved in over 40 years, an FDA expert panel recommends. Currently, allopurinol. Allopurinol (Zyloprim), the most widely prescribed agent for gout in the. compared with allopurinol (versus per 100 patient-years. Since allopurinol is a purine analogue, it also undergoes metabolism by XO, which. serum uric acid levels < 6 (allopurinol, 42% versus febuxostat, 72%).8. oxidase (XO), such as allopurinol (Zyloprim; Aloprim) and febuxostat (Uloric). 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