new/8781-1-2153.php second-generation antipsychotics in children and adolescents with. A placebo-controlled, fixed-dose study of aripiprazole in children and. amoxicillin gentamicin veterinary The CHAT study: clozapine haloperidol aripiprazole trial (2011). or no benefit from treatment with first or second generation antipsychotics. Comparisons of olanzapine with the second generation antipsychotic drugs. Olanzapine was somewhat more efficacious than aripiprazole, quetiapine. the effectiveness of aripiprazole or haloperidol in combination with clozapine for. prescribing a second antipsychotic drug in combination treatment strategies. We expect that the current project, by generating evidence on whether it is. 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