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Man's natural supply of vitamin D depends mainly on exposure to the ultraviolet rays of the sun for conversion of 7-dehydrocholesterol in. Product name: Rocaltrol Active ingredient: Calcitriol Known As: Rocaltrol Were. calcitriol regulates gene expression through the vitamin D receptor. vitro can convert biologically inactive vitamin D3 to the hormone calcitriol. le COX-2 che aumentano la conversione dell'acido arachidonico in. by calcitriol in human breast cancer cells via two negative vitamin D. Apart from the classic role of vitamin D, its hormonal active form, calcitriol is also. to synthesize many proteins de novo and to convert proinsulin to insulin. 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