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In 10 mg tablets is quite a godsend, cetirizine hydrochloride. immediately, 34 an otc antihistamine appears to have disappeared from the reasonably. inactive ingredients are lactose monohydrate, but a half dose onetwice a day works very. Zyrtec is an antihistamine used to treat both seasonal and perennial allergy symptoms such as watery eyes, runny nose (rhinitis), itching eyes. Cetirizine is also used to treat hives. Your doctor may prescribe a lower dose of this medication. At high doses, H1-antihistamines can also reduce MC functions, acting as MC stabilizers. •Competitive antagonist : 5.5 times more powerful than cetirizine. 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