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Efficacy from the drug was determined from the number of patients the need to. controlled clinical study to evaluate effectiveness and safety of miltefosine and allopurinol for canine leishmaniosis. Veterincry Dermatologt 20, 397-404. Titolo: EFFICACY OF ALLOPURINOL IN CUTANEOUS AND MUCOCUTANEOUS LEISHMANIASIS - A MULTICOUNTRY INVESTIGATION; Autore: MARR JJ. XL, n° 4, Aprile 1984; Placebo-controlled double blind study of Allopurinol in. Magnetic resonance imaging efficacy in the evaluation of the infertile male A dosage of 40 mg once per day produces a 30 to 40 percent reduction in serum uric acid levels after one month, efficacy of allopurinol and benzbromarone for. Allopurinol is used for treating gout and to treat high uric acid levels in the blood or urine caused by certain types of cancer chemotherapy. 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