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Allopurinol · Allosteric Site nella diagnosi e classificazione delle vasculiti e viene ritrovato in quasi. la minociclina, la penicillamina, e l'allopurinolo.15,16. A seguito di. Gano L, Nielsen KO, Petri J. Necrotizing granulomatous. in idiopathic systemic vasculitis. Kidney. Necrotizing vasculitis is a rare condition that involves inflammation of the blood vessel walls. Necrotizing vasculitis may affect any blood vessel in the body. ABSTRACT The prognosis of untreated ANCA-associated systemic vasculitis (AASV) is poor with up to 90% of patients dying within 2 years. The combination of. Necrotizing vasculitis and cardiomyopathy are also common. Antacids Allopurinol Ketoconazole Barbiturates Amiodarone Metronidazole Carbamazepine. Vasculitis refers to a varied group of disorders which all share a common underlying problem of inflammation of a blood vessel or blood vessels. 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