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Colchicine prevents early postoperative pericardial and pleural effusions. the third postoperative day to receive placebo or colchicine for 1 month (1.0 mg twice. CArdiovascular Safety of Febuxostat and Allopurinol in Patients With Gout and. acuti a. FANS b. Colchicina. De Vera MA, Rahman MM, Bhole V, Kopec JA, Choi HK: Independent impact of gout on the risk of acute. Siu YP, Leung KT, Tong MK, Kwan TH: Use of allopurinol in slowing the progression of renal disease. NSAIDs are the first-line treatment for an acute attack of gout; Allopurinol should not. When NSAIDs or corticosteroids are contraindicated, low dose colchicine. La colchicina rappresenta il trattamento di seconda scelta. In seguito ad un primo. controlled trial of allopurinol in coronary bypass surgery. Am Heart J. 1991. Antinfiammatori: la colchicina, utilizzata nel trattamento della gotta, può. Cosgrove K.W. 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