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Hospital outbreak of carbapenem-resistant Pseudomonas aeruginosa. the AcrAB multidrug efflux system in intrinsic resistance of Escherichia coli K-12 to β-lactams. Resistance of enterococci to ampicillin and glycopeptide antibiotics in Italy. seriously ill patients, and others in whom infection is suspected and resistance during Primary resistance refers to the intrinsic Table 1 - Incidence of resistance (%) to some drugs in strains isolated from. Finland. cause of their intrinsic nature, experi-. The contribution of penicillin-binding protein 5 (PBP 5) to intrinsic and acquired beta -lactam resistance was investigated by constructing isogenic strains of. Name, Multidrug resistance-associated protein 7. Synonyms, 8051. intrinsic to membrane. integral to membrane. membrane. DB00415, Ampicillin. DB00418. Name, Multidrug resistance-associated protein 5. Synonyms, 8010. intrinsic to membrane. integral to membrane. membrane. DB00415, Ampicillin. 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