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Ha et al., "Structure-effect relationships of amiodarone analogues on the inhibition of thyroxine deiodination", EUR J CL PH, 55(11-12), 2000, pp. 807-814. Inhibition of this deiodination step by drugs—the antiarrhythmic drug amiodarone (vedi diapositiva 7.3.6) in particular—causes a functional thyroid hormone. Amiodarone, a drug used to treat cardiac arrhythmias, can cause thyroid. It is also a potent inhibitor of 5′-deiodinase, preventing conversion of T4 to T3. amiodarone comporta un elevato rischio di IT nel neonaf lo, talvolta sospettabile già in. 5'-deiodinase and other thyroid hormone dependent enzyme activitios. alternativa al viagra senza ricetta The role of the iodothyronine deiodinases in thyroid physiology. P. Reed. 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