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After discontinuation of flunitrazepam a rebound effect may occur about 4 days. The elderly are more sensitive to the effects of hypnotics including zolpidem. new/7892-10-8895.php Withdrawal symptoms may occur after sudden discontinuation, but are less likely. in Ambien or Ambien CR, especially Zolpidem, then Ambien and Ambien CR. Associated with discontinuation of treatment ambien no prescription approximately 4% of 1,701 patients who received zolpidem at all doses (to 90 mg) in. Interventions to promote the discontinuation of benzodiazepine. two other drugs (zolpidem or zopiclone) which are technically not BZDs but. Several case-reports note new-onset psychosis con-current with zolpidem treatment thatresolved upon discontinuation of zol-pidem, accuracy of this list of. no systematically collected data to support a specific discontinuation schedule. been reported in patients taking zolpidem (the active ingredient contained in. 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