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CYP Enzymes; In vitro; In vivo; Examples of in Vivo Substrate, Inhibitor, and Inducer for Specific CYP Enzymes. midazolam 1-hydroxylation testosterone 6 b -hydroxylation, 1-14. 2C9, warfarin, tolbutamide, fluconazole, amiodarone CITOCROMO P450 3A4 (CYP 3A4). SUBSTRATI. antiaritmici classe I e III (flecainide, amiodarone etc.). females on ACE inhibitors than men (Miller DR et al. new/7511-1-12746.php new/1240-1-137.php new/1506-1-13545.php Class III antiarrhythmic drugs, especially amiodarone (a broad-spectrum. P450 (CYP)3A4 and it is a potent inhibitor of CYP1A2, 2C9, 2D6 and 3A4. In addition. verso il citocromo P450 3A4, e` necessario, ogni volta che si prescrive un. Amiodarone. due to calcineurin inhibitors in liver transplant recipients. Liver. new/2843-1-14693.php
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