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Lisinopril can be taken with or without food. like ACE inhibitors, diuretics like furosemide, potassium-sparing diuretics like spironolactone. If you have diabetes, do not use lisinopril together with any medication that. high potassium - nausea, slow or unusual heart rate, weakness, loss of movement;. By inhibiting the production of angiotensin-II, ACE-inhibitors cause vasodilation and indirectly inhibit fluid volume. Potassium-sparing diuretics may have an additive effect on potassium retention, resulting in hyperkalemia. lisinopril: Prinivil. Lisinopril was the third ACE inhibitor (after captopril and enalapril) and was. Therefore, serum potassium, blood pressure, and serum creatinine should be. 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