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Whereas all previously available antipsychotics are antagonists at D2 receptors, aripiprazole is. evidence to make conclusions about mood stabilizers and the anxiolytics. L'uso dei neurolettici determina quindi un calo della dopamina e. basali, aripiprazolo tenderebbe a normalizzare i livelli di prolattina (19, 47. Clinical Efficacy and Dopamine D2 Blockade. Aripiprazole is a partial agonist at DA2 and 5HT1a receptors, claimed to represent a “new generation” of antipsychotics. 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Research within the field of psychopharmacology continues to focus on the development of antipsychotic agents that represent significant improvements over. A group of psychiatric problems that can be categorized as a dopamine. en After having been treated for an acute episode for ‧ weeks and stabilized for an. en In schizophrenia patients the incidence of akathisia was ‧ % with aripiprazole. These medications, referred to as dopamine system stabilizers and exemplified by the prototype drug aripiprazole, sound magical. They are described as. 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