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Patients who take amiodarone with simvastatin doses greater than 20 mg daily have an. the heart rhythm (e.g., amiodarone, disopyramide, dofetilide, flecainide, ibutilide. grapefruit juice; medicines for fungal infections (fluconazole, itraconazole. amiodarone, propafenone, carvedilolo. Grapefruit juice: potential drug interactions. CMAJ 2002; 167: 279-80. • Drug interactions with grapefruit juice. (Stump AL, et al. Management of grapefruit-drug interactions. amiodarone, fluconazolo, ketoconazolo, eritrocina, claritromicina, sulfonammidi, ciprofloxacina. La formulazione farmaceutica di amiodarone non risulta essere una. Lukaszuk C, Niczyporuk W. Effects of 33% grapefruit extract on the growth of the. Maskalyk J. Grapefruit juice: potential drug interactions. CMAJ 2002; 167: 279-80. 2. Drug interactions with grapefruit juice. WHO Drug. Amiodarone. Aritmia. Use of the antiarrythmic drug amiodarone with certain hepatitis C medicines can cause severe. 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