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Building on the discovery that vitamin A can inhibit sebum production at toxic dosages, the retinoic acid derivative isotretinoin (13- cis-retinoic acid) was. new/6865-10-3175.php Taking a vitamin A derivative called Isotretinoin ( Accutane Roaccutane ) did not reduce the risk of second primary tumors or improve survival in patients with. with vitamin E (anti-free radical) and a vitamin C derivative (antioxidan. (in particular isotretinoin), thanks to glycerine, sunflower oleodistillate and ce. viagra autentica Systemic treatment of severe acne with a retinoic acid derivative, isotretinoin. Oral isotretinoin (13-cis-retinoic acid) therapy in severe acne: drug and vitamin A. 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