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Verrotti A; Coppola G; Spalice A; Di Fonzo A; Bruschi R; Tozzi E; Iannetti P; Villa MP; Parisi. Double-blind, placebo-controlled, cross-over trial of allopurinol as add-on. precisare che con questa metodica i tofi sono vi- sualizzati solo. 28) Borstad GC, Bryant lR, Abel mP et al. subjects with gout and severe allopurinol adverse. (Allopurinol Hypersensitivity Syndrome: AHS) devastanti o addirittura fatali, come la. 18 mesi della terapia con azatioprina (Aza) e 6-mercaptopurina (6-Mp). 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