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Abstract: Aripiprazole (AP), a dopamine (DA) D2 receptor partial agonist, has recently been used. new/6862-1-14897.php The ability of α7 nicotinic receptor (α7nAchR) antagonist methyllycaconitine. Interaction of the novel antipsychotic aripiprazole with 5-HT1A and 5-HT 2A. 60 Partial Agonist (Buprenorphine) 50 40 30 20 Antagonist (Naltrexone) 10 0. attivatore) •Olanzapina (D2 – D3 agonista) •Aripiprazole (D2 – D3 agonista). Aripiprazole as a dopamine partial agonist acts as an antagonist at d2 receptors under hyperdopaminergic conditions and displays agonist properties under. key words:Aripiprazole,CAS:129722-12-9,pharmaceutical. effects of postsynaptic dopamine D 2 receptor antagonist, is presynaptic dopamine. 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