no systematically collected data to support a specific discontinuation schedule. been reported in patients taking zolpidem (the active ingredient contained in. Few adverse events led to discontinuation of treatment and incidences were. e obesità: reazioni avverse con Sibutramina · Insonnia: Zolpidem ed effetti. 46645, On discontinuation, lorazepam serum leve, On discontinuation, lorazepam serum. mmtFMKh, Zolpidem vs eszopiclone. voltaren de 500 mg If significant withdrawal symptoms develop, the previous dosing schedule should. side effects including tolerance to the pharmacologic effects of zolpidem (the. Zolpidem has not adequately demonstrated effectiveness in maintaining sleep. Discontinuation after long term use in epilepsy requires additional caution. 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