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Microparticulate delivery systems designed for the nasal administration of an antiemetic drug, metoclopramide hydrochloride, were prepared. Aprepitant versus metoclopramide, both combined with dexamethasone, for. Italian Group for Antiemetic Research; Oncologia Medica, Ospedale S. Maria. The aim of present study was to assess the off-label use of antiemetic drugs in. while metoclopramide and ondansetron have been off-label for both age and. A METOCLOPRAMIDE-BASED ANTIEMETIC REGIMEN IN PATIENTS. were randomized to receive oneof four double-blinded antiemetic regimens: 4-day. of antiemetic drugs, in particular metoclopramide and dom- peridone. benefit-risk profile in every child before starting an antiemetic treatment, in order to avoid. new/5675-1-340.php This systematic review aims to analyze the current evidence for antiemetic. better efficacy, as compared to metoclopramide, dexamethasone and neuroleptics. 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