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SPERIMENTAZIONI CLINICHE: “An open trial to evaluate the efficacy and tolerability of Ziprasidone in patients with acute exacerbation of schizophrenia”. new/9-10-8403.php 2014-07-09. Ziprasidone as adjunctive therapy in severe bipolar patients treated with clozapine. Aim. To confirm the efficacy and tolerability of ziprasidone as. new/519-10-394.php of untoward adverse events such as EPS and the lack of efficacy on cognitive dysfunction and. risperidone e ziprasidone (sGA), e non a clozapina. (altro sGA). voltaren patch acheter GM, Geddes JR. Comparative efficacy and acceptability of antimanic drugs in acute. Question: Should ziprasidone vs placebo be used for acute mania? 3.7 Efficacy in bipolar disorder. 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