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Hypotension with inadequate tissue perfusion should be treated with positive inotropic vasopressor agents. Neither amiodarone nor its metabolite is. L'amiodarone può indurre una cardioversione farmacologica senza. Packer M. The development of positive inotropic agents for chronic. Beta-blocking and amiodarone therapy resulted efficacious in preventing. with opiate addiction, is described in the literature to have cardiac inotropic effects. CTA: Positive and negative predictive value for ischemia. flow, by providing inotropic stimulation or by reducing oxygen. 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