The ampicillin dose is doubled if meningitis is present. Special attention to dosing is required for neonates, who require longer dosing intervals. amoxicillin alternative antibiotics 43.3% neonates were receiving antimicrobials:. Amp + Ctx (if meningitis). Increased risk of death (odds ratio 1.5) with ampicillin +. Lo streptococco risulta sensibile a: penicillina, ampicillina. streptococcal meningitis in infants. Population-based active surveillance for neonatal group B. In early-onset infections, on effective first-line empirical therapy is ampicillin plus an. a combination particularly useful in neonatal meningitis (mean duration of. 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