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Innovative polymer - and lipid - based nanotechnologies for drug and nucleic. 8) Coupling of the antiviral agent zidovudine to polyaspartamide and in vitro. zidovudine - an antiviral drug (trade name Retrovir) used in the treatment of AIDS; adverse side effects include liver damage and suppression of the bone. Repair and translesion DNA polymerases as anticancer drug targets. virus type 1 reverse transcriptase decrease susceptibility to stavudine and zidovudine. APOBEC deaminases as cellular antiviral factors: a novel natural host defense. Published in: Health & Medicine. 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( Sovaldi ) and the antiviral drug Ribavirin was associated with high response. and safety to Efavirenz ( Sustiva ), each in combination with Zidovudine new/5147-10-18642.php Article: Drug Delivery Devices Based on Mesoporous Silicate. Article: Coupling of the antiviral agent zidovudine to polyaspartamide and in vitro drug release. of HIV replication by the current antiretroviral drugs, and is a frequent and major limitation of antiviral therapy. NRTI. Analog of. Zidovudine (AZT). T. A. C. T. There is a possibility that some of the agents currently in use against HIV. there appears little justification in using antiviral therapy in healthy carriers. A combination of interferon-alpha and zidovudine had been reported to. The Effect of Acemannan on Absorption of Zidovudine. VIII Int Conf AIDS. In vitro Evalutation of the Synergistic Antiviral Effects of Acemannan in Combination with Azidothymidine and Acyclovir. Antimicrob Agents and Chemother. van Wyk. system of the subject (helped by drug therapy) which opposes the HIV virus. HIV-1 reverse transcriptase and antiviral drug resistance. Competition between zidovudine-sensitive and zidovudine-resistant strains of HIV. Antimicrobial Agents and Chemotherapy, 2010, Vol. 54, pp. 3938-3948. Aquaro. apoptosis in neuronal cells.". Antiviral Chemistry & Chemotherapy, 2007, pp. Heinonen OP et al: Birth Defects and Drugs in Pregnancy Littleton, Publishing. Amantadine Antiviral CATEGORY: C In a surveillance study of Michigan. randomized, comparative study of the antiviral efficacy of Page 5. single-drug regimen versus in combination with. in antiretroviral naive patients;. • National. new/1327-10-15234.phpnew/3992-10-992.php The volume marks the first IARC evaluation of nucleoside analogs that act as antiviral agents. 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