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Cognitive impairment in breast cancer patients submitted to adjuvant. Impairment of cognitive function in patients submitted to. in. Studio di fattibilità sulle funzioni cognitive nelle pazienti trattate per carcinoma. (2006). Cognitive impairment associated with adjuvant therapy in breast cancer. Letrozolo, Anastrozolo), oppure non sottoposte a terapia ormonale perchè. They purport that anastrozole causes cognitive decline (processing speed and verbal memory) in females taking this medication. However, the authors. Fonte: Ministero della Salute - Italia. Stato dell'autorizzazione: S. Data dell'autorizzazione: 05-12-2008. 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