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Adrenal crisis and severe acute adrenocortical insufficiency are often elusive. steroid use is the most common cause of secondary adrenal. Long-term steroid therapy is the biggest risk factor for adrenal crisis. Oral steroid treatment carries the highest risk; however, inhaled and topical steroids also. Chronic glucocorticoid replacement in adrenal insufficiency. Hahner S, Allolio B Best. Prednisone. 5-7.5 5- 0- 0 mg. Hospitalization for adrenal crisis. L'insufficienza surrenalica primaria (morbo di Addison) è un disordine non comune. in caso di steroidi a lunga durata di azione (prednisone, desametasone) 7. 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