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Ia (procainamide) Ib (lidocaine) Ca channel blocker (verapamil) • Early repolarization hypothesis; 85. 41- The ECG shows a prolonged QT interval (QTC 470 ms). new/6455-10-5137.php A: The QTc interval is markedly prolonged at the peak epinephrine. and reported that verapamil, an ICa-L blocker, shortens the QT and MAP. 7) QT interval and QT dispersion in multiple system atrophy (Shy-Drager syndrome). atrial electrophysiological changes induced by oral verapamil in patients with. 5) Autonomic failure and QT interval prolongation in patients with multiple. rent sustained ventricular tachycardia to verapamil. Br. tional heart disease with prolongation of the QT interval and sudden death. Am Heart. Patients were included with QT interval < or =450 ms, ejection fraction (EF) > or =35%. 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