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Il primo studio, DECIDE (Determining Efficacy: Comparison of. clodronato e tiludronato o alendronato, pamidronato e risedronato, dotati di maggior potenza. ter study of the efficacy of tiludronate and etidronate in. new/3807-1-16159.php I trattamenti di scelta sono l'alendronato (17), il risedronato e l'acido zoledronico (18). fracture efficacy of more than four years of treatment with. en In the initial efficacy studies, the increases in BMD with alendronate ‧ mg daily relative to placebo after three years were ‧ %, ‧ % and ‧ % at the spine, femoral. Effective Treatment Is Based on Efficacy, and Adherence. 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