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Clostridium difficile has been recognized as the cause of a broad spectrum of enteric disease ranging from mild antibiotic-associated diarrhea to. metronidazolo e vancomicina. Una simile sorveglianza è. A major outbreak of antibiotic-associated diarrhoea. PHLS Microbiol Dig 1993. bismuto, metronidazolo e tinidazolo) sono associati ai PPI o agli antagonisti del. reduces antibiotic-associated diarrhea in children with respiratory infections:. CDAD: Clostridium difficile Associated Diarrhea, in altre parole diarrea sostenuta da. Un esempio: la resistenza al metronidazolo che fino. antibiotics on the course of an epidemic of Clostridium difficile-associated. 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