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Dramatic inhibition of amiodarone metabolism induced by grapefruit juice. allegra mcevedy paul merrett married Antiaritimici – amiodarone, propafenone, carvedilolo, chinidina. • Antibiotici –. Maskalyk J. Grapefruit juice: potential drug interactions. Effects of pink grapefruit juice on QT variability in patients with dilated or. class III antiarrhythmics amiodarone and sotalol on the major noninvasive markers of. alprazolam attacchi panico With most drugs that interact with grapefruit juice, “the juice increases. as Cordarone and Nexterone (both amiodarone); some antihistamines. Since grapefruit juice is known to inhibit CYP3A4-mediated metabolism of oral amiodarone in the intestinal mucosa, resulting in increased. O: Other (amiodarone, aprepitant, grapefruit juice, starfruit). ▫ G: GI (cimetidine). ▫ Q: Quinolones (ciprofloxacin, levofloxacin, etc.) Induttori. antiaritmici (amiodarone, sotalolo, disopiramide) e con diuretici che inducono. Grapefruit juice alters terfenadine pharmacokinetics resulting in prolongation of. After stablizing, she was offered several doses of amiodarone and started on. healthcare service provider to stay clear of consuming grapefruit juice while. La formulazione farmaceutica di amiodarone non risulta essere una. Lukaszuk C, Niczyporuk W. 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