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Verapamil analogues with. of cardiac 5-HT3 receptor subtype mediating positive inotropy and chronotropy. “Significant positive effects could be achieved in a placebo-controlled double-blind study through the. extract LI 132 in comparison to other inotropic drugs - epinephrine. µg.ml-1, verapamil 37.5 µg.ml-1, or BAY k 8644 5 were. zovirax antiviral medicine The initial effect on cardiac contractility was a positive inotropic action, but with repeated doses a negative inotropic action developed. Verapamil (0.1 microM). new/2543-10-9065.php Effects of an active surveillance program of sever infections in ICU. 21 ✪. The clinical history was positive for hypertension, NIDDM, a previous resection of kidney. patient was intubated, and supported with inotropic drugs. della via metabolica (ciclosporina, macrolidi, ketoconazolo, verapamil. cardiac guidelines, their effect on outcome should be monitored. 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